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Figure 4 | Journal of Orthopaedic Surgery and Research

Figure 4

From: Isoflavones prevent bone loss following ovariectomy in young adult rats

Figure 4

Mean bone porosity after ovariectomy and treatment with and without isoflavone-rich diet. In the normal rats (Group A), the mean bone porosity was 76.7%, 79.1%, and 74.3% for the femur, spine, and tibia, respectively. After ovariectomy (Group B), the mean bone porosities significantly increased to 89.8%, 89.2%, and 85.7% for the femur, spine, and tibia, respectively (P < 0.05). The bone porosities of group C (an isoflavone-rich diet for one month followed by ovariectomy and a normal diet) significantly increased to 85.8%, 86.9%, and 88.2% in the femur, spine, and tibia, repectively, while in Group D (an isoflavone-rich diet for three months), the bone porosities of the femur, spine, and tibia decreased to 59.3%, 66.8%, and 64.0%, respectively, two months after ovariectomy (P < 0.05). Ovariectomy increases, while an isoflavone-rich diet decreases bone porosity.

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