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Figure 3 | Journal of Orthopaedic Surgery and Research

Figure 3

From: Proliferating and differentiating effects of three different growth factors on pluripotent mesenchymal cells and osteoblast like cells

Figure 3

a) Cell count of the pluripotent mesenchymal cell line (C2C12) treated with different growth factors. The data presented are normalized to the control group (PDLLA) which is set 100%. A significant increase in the cell number was seen after treatment with PDGFbb, IGF-I or BMP-2 in comparison to the PDLLA treated cells (ANOVA, Dunnett). b) Alkaline phosphatase activity (AP) of pluripotent mesenchymal cell line (C2C12) treated with different growth factors. The data presented are normalized to the control group (PDLLA) which is set 100%. A significant increase in AP activity was seen after treatment with BMP-2 in comparison to the PDLLA treated cells (ANOVA, Dunnett). c) Migration assay of C2C12 cells. A significant migration was detectable in the control group (10% FCS) but not in the growth factor groups.

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