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Figure 2 | Journal of Orthopaedic Surgery and Research

Figure 2

From: Elevated adipogenesis of marrow mesenchymal stem cells during early steroid-associated osteonecrosis development

Figure 2

Blood perfusion assessed by dynamic MRI for Maximum Enhancement and Time-Signal Intensity. (A) Maximum Enhancement at the examined sites (both proximal femora and distal femora, the similar pattern was found, data not shown here for distal femora) showed a significant decrease from baseline in ON+ rabbits at week 2 after steroid induction. There were significant decrease in Maximum Enhancement between ON+ and ON-group, MON and SON group at week 2 (p < 0.05). (B) Representative Time-Signal Intensity curves from contrast-enhanced dynamic MRI on proximal femur. The Time-Signal Intensity curve showed a significant decrease in enhancement slope in ON+ group as compared with ON- group at week 2.

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